Altered expression of serum miR-106a, miR-19b, miR-17, and PTEN in patients with idiopathic membranous nephropathy

Altered expression of serum miR-106a, miR-19b, miR-17, and PTEN in patients with idiopathic membranous nephropathy

Background: To find new diagnostic markers for idiopathic membranous nephropathy (IMN) and also conduct preliminary explorations into the possible pathogenesis of IMN by comparing the expression of microRNA-451a (miR-451a), miR-106a, miR-19b, miR-17, and phosphatase and tensin homolog (PTEN) protein...

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Bibliographic Details
Main Authors: Li, X. (Author), Liu, Y. (Author), Luo, L. (Author), Qin, X. (Author), Wu, L. (Author), Zhang, X. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
adult
albuminoid
Albumins
Article
blood
case control study
Case-Control Studies
complication
concentration (parameter)
controlled study
creatinine
Creatinine
creatinine blood level
cystatin C
Cystatin C
DNA synthesis
enzyme linked immunosorbent assay
estimated glomerular filtration rate
female
Female
gene expression
gene expression regulation
Gene Expression Regulation
genetic analysis
genetics
Glomerular Filtration Rate
Glomerulonephritis, Membranous
glomerulus filtration rate
human
Humans
idiopathic membranous nephropathy
major clinical study
male
Male
membranous glomerulonephritis
metabolism
microRNA
microRNA 106a
microRNA 17
microRNA 19b
microRNA-106a
microRNA-17
microRNA-19b
microRNA-451a
MicroRNAs
middle aged
Middle Aged
MIRN106 microRNA, human
MIRN17 microRNA, human
MIRN19 microRNA, human
pathogenesis
pathophysiology
phosphatase and tensin homolog protein
phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase
protein urine level
proteinuria
Proteinuria
PTEN Phosphohydrolase
PTEN protein, human
real time polymerase chain reaction
RNA extraction
unclassified drug
urea
Urea
urea blood level
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