A novel CD209 polymorphism is associated with rheumatoid arthritis patients in Taiwan

A novel CD209 polymorphism is associated with rheumatoid arthritis patients in Taiwan

Single nucleotide polymorphisms (SNPs) in the promoter region of CD209 (cluster of differentiation 209) may influence expression levels, and higher expression of CD209 on immune cells correlate with severity of cartilage destruction in patients with rheumatoid arthritis (RA). Due to the lack of a co...

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Bibliographic Details
Main Authors: Chan, H.-C (Author), Li, R.-N (Author), Lin, C.-H (Author), Lin, Y.-Z (Author), Wang, S.-C (Author), Yen, J.-H (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
abatacept
adult
allele
Alleles
Arthritis, Rheumatoid
Article
autoimmunity
Base Sequence
biological therapy
case control study
Case-Control Studies
CD209 antigen
CD209 gene
CD209 polymorphism
cell adhesion molecule
Cell Adhesion Molecules
cell surface receptor
controlled study
DC-specific ICAM-3 grabbing nonintegrin
female
Female
gene amplification
gene frequency
Gene Frequency
gene linkage disequilibrium
genetic association
Genetic Association Studies
genetic association study
genetic predisposition
Genetic Predisposition to Disease
genetic variability
genetics
genomic DNA
genotype
haplotype
Haplotypes
human
human cell
Humans
lectin
Lectins, C-Type
Linkage Disequilibrium
major clinical study
male
Male
middle aged
Middle Aged
nucleotide sequence
peripheral blood mononuclear cell
Polymorphism, Single Nucleotide
promoter region
Promoter Regions, Genetic
Receptors, Cell Surface
rheumatoid arthritis
rituximab
Sanger sequencing
single nucleotide polymorphism
Taiwan
Taiwanese
tocilizumab
tumor necrosis factor inhibitor
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