A combination of ssGSEA and mass cytometry identifies immune microenvironment in muscle-invasive bladder cancer

Background: Muscle-invasive bladder cancer (MIBC) is a heterogeneous disease with varying clinical courses and responses to treatment. To improve the prognosis of patients, it is necessary to understand such heterogeneity. Methods: We used single-sample gene set enrichment analysis to classify 35 MI...

Full description

Bibliographic Details
Main Authors:	Feng, C. (Author), Hu, J. (Author), Huang, H. (Author), Lai, Z. (Author), Li, T. (Author), Li, Z. (Author), Lu, Q. (Author), Pan, L. (Author), Tang, Z. (Author), Tao, Y. (Author), Wang, Q. (Author), Wang, X. (Author), Xie, Y. (Author)
Format:	Article
Language:	English
Published:	John Wiley and Sons Inc 2021
Subjects:	Article B lymphocyte bioinformatics bladder tumor cancer therapy carcinogenesis cell function cell heterogeneity cell infiltration cell subpopulation clinical article comparative study controlled study cytotoxic T lymphocyte cytotoxicity dendritic cell flow cytometry Flow Cytometry gene expression assay gene expression profiling Gene Expression Profiling gene expression regulation Gene Expression Regulation, Neoplastic gene ontology gene set enrichment analysis genetics helper cell hepatitis A virus cellular receptor 2 human human cell human tissue Humans immune microenvironment immune response immunology immunophenotyping Immunophenotyping immunosignature Immunosuppression immunosuppressive treatment M2 macrophage mass cytometry muscle muscle invasive bladder cancer muscle-invasive bladder cancer Muscles natural killer cell Neoplasm Invasiveness pathology prognosis programmed death 1 receptor protein expression receptor type tyrosine protein phosphatase C regulatory T lymphocyte signal transduction single sample gene set enrichment analysis ssGSEA tumor associated leukocyte tumor heterogeneity tumor immunity tumor invasion tumor marker tumor microenvironment Tumor Microenvironment upregulation Urinary Bladder Neoplasms
Online Access:	View Fulltext in Publisher

Internet

View Fulltext in Publisher

A combination of ssGSEA and mass cytometry identifies immune microenvironment in muscle-invasive bladder cancer

Internet

Similar Items