The clinical significance of spondin 2 eccentric expression in peripheral blood mononuclear cells in bronchial asthma

Background: Bronchial asthma (BA) was a heterogeneous disease characterized by chronic airway inflammation. Spondin 2 (SPON2) was reported to be implicated in the integrin pathway, protein metabolism, and drug-induced lupus erythematosus. The purpose of this study was to evaluate the significance of...

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Bibliographic Details
Main Authors:	Wei, J.-F (Author), Xiang, C.-X (Author), Zhou, P. (Author)
Format:	Article
Language:	English
Published:	John Wiley and Sons Inc 2021
Subjects:	adolescent Adolescent Area Under Curve area under the curve Article asthma Asthma bioinformatics biological marker blood blood sampling bronchial asthma case control study Case-Control Studies cell isolation child Child controlled study degranulation diagnosis disease severity enzyme linked immunosorbent assay eosinophil Extracellular Matrix Proteins female Female forced expiratory volume Forced Expiratory Volume forced vital capacity fractional exhaled nitric oxide gene expression Gene Expression genetics GO analysis human Humans immunity immunoglobulin E Immunoglobulin E interleukin 12 interleukin 13 interleukin 17 interleukin 4 interleukin derivative Interleukins leukocyte activation Leukocytes, Mononuclear lung ventilation major clinical study male Male membrane protein mononuclear cell Neoplasm Proteins neutrophil pathogenesis pathology patient acuity Patient Acuity peripheral blood mononuclear cell physiology protein expression protein KDM5D protein OLFM4 protein RPS4Y1 protein TSIX protein XIST real time polymerase chain reaction receiver operating characteristic scleroprotein SPON2 protein, human spondin 2 tumor protein unclassified drug upregulation
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The clinical significance of spondin 2 eccentric expression in peripheral blood mononuclear cells in bronchial asthma

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