COVID-19 spreading across world correlates with C677T allele of the methylenetetrahydrofolate reductase (MTHFR) gene prevalence

COVID-19 spreading across world correlates with C677T allele of the methylenetetrahydrofolate reductase (MTHFR) gene prevalence

Background: Homocysteine assessment has been proposed as a potential predictive biomarker for the severity of COVID-19 infection. The purpose of this review was to analyze the correlation between the prevalence of MTHFR C677 T gene polymorphism and COVID-19 incidence and mortality worldwide. Methods...

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Bibliographic Details
Main Authors: Iannella, R. (Author), Kaleci, S. (Author), Manfredini, M. (Author), Oliva, G. (Author), Ozben, T. (Author), Pastorino, L. (Author), Ponti, G. (Author), Tomasi, A. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
5,10 methylenetetrahydrofolate reductase (FADH2)
allele
Alleles
Article
C677 T mutation prevalence
C677T gene
coronavirus disease 2019
correlational study
COVID-19
COVID-19 vulnerability
disease predisposition
disease severity
disease transmission
enzymology
epidemiology
ethnic group
Ethnic Groups
gene
gene frequency
Gene Frequency
gene mutation
genetic correlation
genetic polymorphism
genetic predisposition
Genetic Predisposition to Disease
genetic variability
genetics
Hispanic
Homocysteine
homocysteine metabolism
human
Humans
incidence
metabolism
methylenetetrahydrofolate reductase (NADPH2)
Methylenetetrahydrofolate Reductase (NADPH2)
mortality
mortality rate
MTHFR gene
predictive value
prevalence
Prevalence
trend study
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