tRNAIniCAT inhibits proliferation and promotes apoptosis of laryngeal squamous cell carcinoma cells

tRNAIniCAT inhibits proliferation and promotes apoptosis of laryngeal squamous cell carcinoma cells

Background: Laryngeal squamous cell carcinoma (LSCC) brings a heavy blow to the patient's voice. Transfer RNA (tRNA) is a common RNA, the roles of tRNAs in LSCC are largely unknown. Methods: The tRNA expression profile in LSCC tissues and adjacent normal tissues was measured by a tRNA qRT-PCR a...

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Bibliographic Details
Main Authors: Deng, H. (Author), Gu, S. (Author), Li, J. (Author), Luo, L. (Author), Shen, Z. (Author), Ye, D. (Author), Zhou, C. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
animal
animal experiment
animal model
animal tissue
Animals
apoptosis
Apoptosis
area under the curve
Article
Bagg albino mouse
biomarkers
blood
cancer growth
Carcinoma, Squamous Cell
Cell Line, Tumor
cell proliferation
Cell Proliferation
controlled study
down regulation
drug screening
female
Female
gene expression
gene expression profiling
Gene Expression Profiling
gene expression regulation
Gene Expression Regulation, Neoplastic
genetics
green fluorescent protein
Green Fluorescent Proteins
human
human cell
Humans
in vitro study
in vivo study
Laryngeal Neoplasms
laryngeal squamous cell carcinoma
laryngeal squamous cell carcinoma cell line
larynx tumor
metabolism
Mice, Inbred BALB C
Mice, Nude
mouse
nonhuman
nude mouse
pathology
real time polymerase chain reaction
receiver operating characteristic
RNA, Transfer
ROC Curve
squamous cell carcinoma
transfer RNA
transmission electron microscopy
tRNA
tRNA expression profile
tRNAIniCAT
tumor cell line
tumor xenograft
upregulation
Up-Regulation
Xenograft Model Antitumor Assays
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