Lower expression of Hsa_circRNA_102682 in diabetic hyperhomocysteinemia negatively related to creatinemia is associated with TGF-β and CTGF

Background: Diabetic nephropathy is a kidney disease caused by long-term hyperglycemia. Hsa_circRNA_102682 is related to the pathogenesis of preeclampsia. Preeclampsia is related to hypertension and proteinuria, and diabetic nephropathy is mainly manifested by hypertension and proteinuria. The main...

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Bibliographic Details
Main Authors:	Bu, S. (Author), Chu, Y. (Author), Dai, H. (Author), Hu, F. (Author), Hu, P. (Author), Qiu, X. (Author), Sha, W. (Author), Yang, X. (Author)
Format:	Article
Language:	English
Published:	John Wiley and Sons Inc 2021
Subjects:	abnormal substrate concentration in blood adult Article blood CCN2 protein, human circular ribonucleic acid circular RNA connective tissue growth factor Connective Tissue Growth Factor controlled study creatinemia creatinine Creatinine creatinine blood level CTGF diabetic hyperhomocysteinemia Diabetic Nephropathies diabetic nephropathy diagnostic test accuracy study diagnostic value enzyme linked immunosorbent assay gene expression gene expression regulation Gene Expression Regulation gene function genetics homocysteine Homocysteine Hsa_circRNA_102682 human Humans hyperhomocysteinemia Hyperhomocysteinemia major clinical study middle aged Middle Aged predictive value protein blood level real time reverse transcription polymerase chain reaction receiver operating characteristic risk factor RNA analysis RNA, Circular ROC Curve TGF-β transforming growth factor beta Transforming Growth Factor beta
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Lower expression of Hsa_circRNA_102682 in diabetic hyperhomocysteinemia negatively related to creatinemia is associated with TGF-β and CTGF

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