Establishment of time-resolved fluoroimmunoassay of IgG4 based on magnetic microspheres

Establishment of time-resolved fluoroimmunoassay of IgG4 based on magnetic microspheres

Background: The abnormal increase in serum IgG4 level is an important clinical symptom of IgG4-related disease (IgG4-RD), and the detection of serum IgG4 level is a powerful tool for the diagnosis of IgG4-RD. This study was conducted to establish a simple and rapid immunoassay for the determination...

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Bibliographic Details
Main Authors: Hang, C. (Author), Huang, B. (Author), Huang, P. (Author), Li, T. (Author), Qin, Y. (Author), Sheng, H. (Author), Wang, B. (Author), Wang, Y. (Author), Wu, Q. (Author), Xia, P. (Author), Zhou, X. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
Antibodies
antibody
Article
blood
blood analysis
Blood Chemical Analysis
clinical article
controlled study
devices
europium
Europium
Fluoroimmunoassay
human
Humans
IgG4
IgG4-RD
immunoassay
immunofluorescence assay
immunoglobulin blood level
immunoglobulin G
Immunoglobulin G
immunoglobulin G4
immunonephelometry
intermethod comparison
limit of detection
Limit of Detection
magnetic field
magnetic microsphere
magnetic microspheres
Magnetic Phenomena
magnetism
measurement
measurement accuracy
measurement precision
microsphere
Microspheres
procedures
process optimization
sensitivity analysis
sensitivity and specificity
Sensitivity and Specificity
time resolved immunofluorescence assay
time-resolved fluorescence immunoassay
unclassified drug
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