The Hologic Aptima SARS-CoV-2 assay enables high ratio pooling saving reagents and improving turnaround time

The Hologic Aptima SARS-CoV-2 assay enables high ratio pooling saving reagents and improving turnaround time

Background: The Hologic Aptima™ TMA SARS-CoV-2 assay was employed to test pooled nasopharyngeal (NP) samples to evaluate the performance of pooled sample testing and characterize variables influencing results. Methods: Results on 1033 previously tested NP samples were retrieved to characterize the r...

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Bibliographic Details
Main Authors: Chamala, S. (Author), Clare-Salzler, M. (Author), Martinez, K. (Author), Newsom, K. (Author), Starostik, P. (Author), Zhang, Y. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
article
comparative study
controlled study
COVID-19
COVID-19 Testing
devices
diagnosis
False Negative Reactions
false negative result
genetics
human
Humans
isolation and purification
major clinical study
mass screening
Mass Screening
nasopharynx
Nasopharynx
nonhuman
polymerase chain reaction
pooling samples
procedures
reproducibility
Reproducibility of Results
Reverse Transcriptase Polymerase Chain Reaction
reverse transcription polymerase chain reaction
SARS-CoV-2
screening test
Severe acute respiratory syndrome coronavirus 2
transcription-mediated amplification
turnaround time
virology
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