Vitamin D level, lipid profile, and vitamin D receptor and transporter gene variants in sickle cell disease patients from Kurdistan of Iraq

Introduction: Sickle cell disease (SCD) patients are susceptible to the development of vitamin D deficiency (VDD). Vitamin D through binding to vitamin D receptor (VDR) exerts its function and affects gene transcription in target tissues. VDR gene variants affect bone mineral density. Methods: In a...

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Bibliographic Details
Main Authors:	Abdulkarim, O.A (Author), Hama, A.H (Author), Karimi, M. (Author), Mozafari, H. (Author), Rahimi, Z. (Author), Shakiba, E. (Author)
Format:	Article
Language:	English
Published:	John Wiley and Sons Inc 2021
Subjects:	adenine adolescent Adolescent allele Anemia, Sickle Cell Article beta thalassemia beta-Thalassemia biological marker Biomarkers blood bone density calcitriol receptor case control study Case-Control Studies child Child cholesterol cholesterol blood level controlled study cytosine female Female GC genetic polymorphism genetic variability genetics genotyping guanine high density lipoprotein cholesterol human Humans hypocholesterolemia Iraq lipid lipid fingerprinting lipid profile Lipids low density lipoprotein cholesterol major clinical study male Male polymerase chain reaction restriction fragment length polymorphism Polymorphism, Genetic prevalence Receptors, Calcitriol SCD sickle cell anemia single nucleotide polymorphism thymine triacylglycerol VDR FokI VDR protein, human VDR TaqI vitamin D Vitamin D vitamin D receptor
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Vitamin D level, lipid profile, and vitamin D receptor and transporter gene variants in sickle cell disease patients from Kurdistan of Iraq

Internet

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