Chaperonin-containing tailless complex polypeptide 1 subunit 6A correlates with increased World Health Organization grade, less isocitrate dehydrogenase mutation, and deteriorative survival of astrocytoma patients

Objective: Chaperonin-containing tailless complex polypeptide 1 subunit 6A (CCT6A) is reported to be an efficient prognostic biomarker in various cancers, but it is rarely reported in astrocytoma. Thus, this study aimed to evaluate the expression of CCT6A and its correlation with disease features an...

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Bibliographic Details
Main Authors:	Fu, P. (Author), Hu, Y. (Author), Jiang, X. (Author), Lv, P. (Author), Zhang, F. (Author), Zhao, H. (Author), Zhao, W. (Author)
Format:	Article
Language:	English
Published:	John Wiley and Sons Inc 2021
Subjects:	adjuvant radiotherapy adjuvant therapy adult antineoplastic agent Article astrocytoma Astrocytoma Biomarkers, Tumor brain surgery cancer adjuvant therapy cancer grading cancer patient cancer prognosis cancer radiotherapy cancer surgery cancer survival cancer tissue CCT6A protein, human chaperonin containing tailless complex polypeptide 1 subunit 6A chaperonin containing TCP1 Chaperonin Containing TCP-1 chaperonin-containing tailless complex polypeptide 1 subunit 6A clinical feature controlled study correlational study diagnostic accuracy diagnostic test accuracy study female Female follow up Follow-Up Studies formaldehyde frozen section gene expression gene mutation genetics human human tissue Humans IDH gene IDH1 protein, human IDH2, human immunohistochemistry isocitrate dehydrogenase Isocitrate Dehydrogenase isocitrate dehydrogenase mutation liquid nitrogen major clinical study male Male messenger RNA metabolism middle aged Middle Aged mortality mutation Mutation overall survival paraffin embedding pathology prediction prognosis Prognosis protein expression real time reverse transcription polymerase chain reaction reference value Retrospective Studies retrospective study scoring system survival rate Survival Rate tumor marker unclassified drug World Health Organization World Health Organization grade
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Chaperonin-containing tailless complex polypeptide 1 subunit 6A correlates with increased World Health Organization grade, less isocitrate dehydrogenase mutation, and deteriorative survival of astrocytoma patients

Internet

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