Performance evaluation of three automated quantitative immunoassays and their correlation with a surrogate virus neutralization test in coronavirus disease 19 patients and pre-pandemic controls

Performance evaluation of three automated quantitative immunoassays and their correlation with a surrogate virus neutralization test in coronavirus disease 19 patients and pre-pandemic controls

Background: SARS-CoV-2 pandemic is currently ongoing, meanwhile vaccinations are rapidly underway in some countries. The quantitative immunoassays detecting antibodies against spike antigen of SARS-CoV-2 have been developed based on the findings that they have a better correlation with the neutraliz...

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Bibliographic Details
Main Authors: Hong, Y.J (Author), Jung, K. (Author), Nam, M. (Author), Park, K.U (Author), Roh, E.Y (Author), Shin, S. (Author), Song, E.Y (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
Antibodies, Neutralizing
Antibodies, Viral
Article
automation
blood
blood analysis
comparative study
controlled study
coronavirus disease 2019
coronavirus spike glycoprotein
COVID-19
COVID-19 Serological Testing
devices
female
human
Humans
immunoassay
Immunoassay
immunoassays
immunoglobulin G
Immunoglobulin G
immunology
infection control
intermethod comparison
major clinical study
male
Neutralization Tests
neutralizing antibody
procedures
process development
quantitative assay
receiver operating characteristic
reproducibility
Reproducibility of Results
ROC Curve
SARS-CoV-2
sensitivity and specificity
Sensitivity and Specificity
serodiagnosis
Serologic Tests
serology
Severe acute respiratory syndrome coronavirus 2
spike antigen
Spike Glycoprotein, Coronavirus
spike protein, SARS-CoV-2
virology
virus antibody
virus neutralization
virus neutralization test
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