METTL3-mediated m6A methylation of ASPM drives hepatocellular carcinoma cells growth and metastasis

Background: Abnormal spindle-like microcephaly (ASPM) has been proved to participate in tumor progression. However, the underlying mechanism of ASPM in liver hepatocellular carcinoma (LIHC) remains elusive. Methods: The mRNA and protein expression were determined using Western blot and qRT-PCR, and...

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Bibliographic Details
Main Authors: Chen, X. (Author), Jiang, J. (Author), Li, D. (Author), Wang, A. (Author), Yang, L. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
m6A
Online Access:View Fulltext in Publisher