Kinetics of platelet adhesion to a fibrinogen-coated surface in whole blood under flow conditions

Kinetics of platelet adhesion to a fibrinogen-coated surface in whole blood under flow conditions

Aim: To test a novel method of assessment of platelet adhesion to a fibrinogen-coated surface in whole blood under flow conditions. Methods: We developed a fluidic device that mimics blood flow in vessels. The method of detection of platelet adhesion is based on recording of a scattered laser light...

Full description

Bibliographic Details
Main Authors: Avtaeva, Y.N (Author), Caprnda, M. (Author), Gabbasov, Z.A (Author), Kruzliak, P. (Author), Melnikov, I.S (Author), Mozos, I. (Author), Okhota, S.D (Author), Prosecky, R. (Author), Rodrigo, L. (Author), Zozulya, N.I (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
adult
amino acid sequence
antithrombocytic agent
Article
autoimmune thrombocytopenia
blood flow
Blood Platelets
coating (procedure)
controlled study
fibrinogen
Fibrinogen
fibrinogen receptor
fibrinogen-coated surface
flow conditions
glycoprotein Ib receptor
Healthy Volunteers
human
human cell
Humans
kinetics
Kinetics
light intensity
light scattering
measurement
metabolism
middle aged
normal human
platelet adhesion
Platelet Adhesiveness
Platelet Aggregation
Platelet Aggregation Inhibitors
Platelet Glycoprotein GPIb-IX Complex
Platelet Glycoprotein GPIIb-IIIa Complex
receptor
receptor blocking
recording of a scattered laser light signal from a fibrinogen-covered surface
thrombin receptor
thrombocyte
thrombocyte adhesion
thrombocyte aggregation
thrombocyte kinetics
thrombocyte rich plasma
unclassified drug
volunteer
von Willebrand disease
whole blood
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items