IL-23/IL-17 axis and soluble receptors isoforms sIL-23R and sIL-17RA in patients with rheumatoid arthritis-presenting periodontitis

IL-23/IL-17 axis and soluble receptors isoforms sIL-23R and sIL-17RA in patients with rheumatoid arthritis-presenting periodontitis

Background: Rheumatoid arthritis (RA) and periodontitis (P) are chronic inflammatory diseases characterized by joint and radiographic bone loss, respectively. IL-23 and IL-17 have an essential role in the immunopathogenesis of RA, and P. IL-23 stimulates Th17 cells through which produces IL-17, IL-2...

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Bibliographic Details
Main Authors: Bernard-Medina, A.G (Author), Gómez-Meda, B.C (Author), Guerrero-Velázquez, C. (Author), Martínez-Rodríguez, V.M.D.C (Author), Oregon-Romero, E. (Author), Pita-López, M.L (Author), Rodríguez-Montaño, R. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
adult
Adult
Arthritis, Rheumatoid
Article
biological marker
Biomarkers
blood
blood sampling
C reactive protein
case control study
Case-Control Studies
chi square test
complication
controlled study
correlation coefficient
Cross-Sectional Studies
cross-sectional study
DAS28
disease classification
enzyme linked immunosorbent assay
erythrocyte sedimentation rate
female
Female
Health Assessment Questionnaire
Health Assessment Questionnaire Disability Index
human
Humans
IL-17A
IL17A protein, human
IL17RA protein, human
IL-23
IL23A protein, human
IL23R protein, human
interleukin 17
interleukin 17 receptor
interleukin 17 receptor A
interleukin 23
interleukin 23 receptor
interleukin 23p19
interleukin receptor
Interleukin-17
Interleukin-23 Subunit p19
major clinical study
male
Male
pathology
periodontitis
Periodontitis
prognosis
Prognosis
protein blood level
protein expression
rank sum test
Receptors, Interleukin
Receptors, Interleukin-17
rheumatoid arthritis
rheumatoid arthritis-presenting periodontitis
rheumatoid factor
sIL-17RA
sIL-23R
staging
swollen joint count
tender joint count
unclassified drug
visual analog scale
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