IL-23/IL-17 axis and soluble receptors isoforms sIL-23R and sIL-17RA in patients with rheumatoid arthritis-presenting periodontitis

IL-23/IL-17 axis and soluble receptors isoforms sIL-23R and sIL-17RA in patients with rheumatoid arthritis-presenting periodontitis

Background: Rheumatoid arthritis (RA) and periodontitis (P) are chronic inflammatory diseases characterized by joint and radiographic bone loss, respectively. IL-23 and IL-17 have an essential role in the immunopathogenesis of RA, and P. IL-23 stimulates Th17 cells through which produces IL-17, IL-2...

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Bibliographic Details
Main Authors:	Bernard-Medina, A.G (Author), Gómez-Meda, B.C (Author), Guerrero-Velázquez, C. (Author), Martínez-Rodríguez, V.M.D.C (Author), Oregon-Romero, E. (Author), Pita-López, M.L (Author), Rodríguez-Montaño, R. (Author)
Format:	Article
Language:	English
Published:	John Wiley and Sons Inc 2021
Subjects:	adult Adult Arthritis, Rheumatoid Article biological marker Biomarkers blood blood sampling C reactive protein case control study Case-Control Studies chi square test complication controlled study correlation coefficient Cross-Sectional Studies cross-sectional study DAS28 disease classification enzyme linked immunosorbent assay erythrocyte sedimentation rate female Female Health Assessment Questionnaire Health Assessment Questionnaire Disability Index human Humans IL-17A IL17A protein, human IL17RA protein, human IL-23 IL23A protein, human IL23R protein, human interleukin 17 interleukin 17 receptor interleukin 17 receptor A interleukin 23 interleukin 23 receptor interleukin 23p19 interleukin receptor Interleukin-17 Interleukin-23 Subunit p19 major clinical study male Male pathology periodontitis Periodontitis prognosis Prognosis protein blood level protein expression rank sum test Receptors, Interleukin Receptors, Interleukin-17 rheumatoid arthritis rheumatoid arthritis-presenting periodontitis rheumatoid factor sIL-17RA sIL-23R staging swollen joint count tender joint count unclassified drug visual analog scale
Online Access:	View Fulltext in Publisher

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