Assessment of antiphospholipid antibodies and calprotectin as biomarkers for discriminating mild from severe COVID-19

Background: To explore the association of thrombo-inflammatory biomarkers with severity in coronavirus disease (COVID-19), we measured antiphospholipid antibodies (aPL) and calprotectin in sera of COVID-19 patients. Methods: Anticardiolipin antibodies (aCL) and anti-β2-glycoprotein I antibodies were...

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Bibliographic Details
Main Authors:	Lee, A. (Author), Lee, J.-S (Author), Lee, K.-R (Author), Lee, M.-K (Author), Nahm, C.H (Author)
Format:	Article
Language:	English
Published:	John Wiley and Sons Inc 2021
Subjects:	adult adult respiratory distress syndrome aged Aged Aged, 80 and over Antibodies, Antiphospholipid antibody antibody titer anticardiolipin antibodies antiphospholipid antibodies Article beta2 glycoprotein 1 antibody biological marker Biomarkers blood C reactive protein calgranulin calprotectin cardiolipin antibody CD4 antigen CD4+ T lymphocyte controlled study coronavirus disease 2019 COVID-19 C-Reactive Protein diagnosis diagnostic test accuracy study disease severity enzyme linked immunosorbent assay female Female ferritin hospitalization human Humans immunoassay immunoglobulin M Leukocyte L1 Antigen Complex limit of detection lymphocyte count major clinical study male Male middle aged Middle Aged neutrophil lymphocyte ratio nitrogen oxygenation phosphatidylserine phosphatidylserine antibody phospholipid antibody procalcitonin prothrombin antibody receiver operating characteristic retrospective study SARS-CoV-2 sensitivity and specificity severity severity of illness index Severity of Illness Index unclassified drug urea urea nitrogen blood level very elderly Youden index
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Assessment of antiphospholipid antibodies and calprotectin as biomarkers for discriminating mild from severe COVID-19

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