Drug metabolism-related eight-gene signature can predict the prognosis of gastric adenocarcinoma

Drug metabolism-related eight-gene signature can predict the prognosis of gastric adenocarcinoma

Background: Metabolic abnormalities in patients with gastric adenocarcinoma lead to drug resistance and poor prognosis. Therefore, this study aimed to explore biomarkers that can predict the prognostic risk of gastric adenocarcinoma by analyzing drug metabolism-related genes. Methods: The RNA-seq an...

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Bibliographic Details
Main Authors: Chen, J. (Author), He, Q. (Author), Hu, X. (Author), Li, Z. (Author), Yang, W. (Author), Yin, H.-M (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
ABCA1 gene
adenocarcinoma
Adenocarcinoma
ADH4 gene
adult
Adult
aged
Aged
antineoplastic agent
Article
Biomarkers, Tumor
cancer prognosis
cancer survival
chemistry
DHRS7 gene
drug binding
drug effect
drug inactivation
drug metabolism
gastric adenocarcinoma
gene
gene expression
gene targeting
genetics
glibenclamide
Glyburide
GPX3 gene
human
Humans
hydrogen
immune microenvironment
immunology
Inactivation, Metabolic
metabolism
miconazole
Miconazole
middle aged
Middle Aged
molecular docking
Molecular Docking Simulation
mortality
nicotinic acid
NNMT gene
nomogram
Nomograms
NOS3 gene
predictive value
prognosis
Prognosis
prognostic model
protein
protein analysis
Protein Interaction Maps
Proteins
reproducibility
Reproducibility of Results
risk factor
Risk Factors
SLCO4A1 gene
stomach adenocarcinoma
Stomach Neoplasms
stomach tumor
TAP1 gene
tumor marker
tumor microenvironment
Tumor Microenvironment
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