Long noncoding RNA TUG1 upregulates VEGFA to enhance malignant behaviors in stomach adenocarcinoma by sponging miR-29c-3p

Background: Long noncoding RNA (lncRNA) TUG1 has been reported to display a pivotal role in the tumorigenesis and malignant progression of various types of cancers, including stomach adenocarcinoma (STAD). However, the contribution of aberrant expression of TUG1 and the mechanism by which it serves...

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Bibliographic Details
Main Authors:	Cao, J. (Author), Cheng, H. (Author), Hu, X. (Author), Jin, Y. (Author)
Format:	Article
Language:	English
Published:	John Wiley and Sons Inc 2021
Subjects:	adenocarcinoma Adenocarcinoma angiogenesis animal animal experiment animal model animal tissue Animals Article Bagg albino mouse bioinformatics Cell Line, Tumor cell migration cell motion Cell Movement cell proliferation Cell Proliferation controlled study drug screening gastric adenocarcinoma cell line gene expression gene expression regulation Gene Expression Regulation, Neoplastic gene overexpression genetics human human cell Humans in vitro study in vivo study long untranslated RNA male Male metabolism Mice, Inbred BALB C microRNA MicroRNAs miR 29c 3p miR-29c-3p MIRN29C microRNA, human mouse neovascularization (pathology) Neovascularization, Pathologic nonhuman oncogene pathology protein RNA binding RNA, Long Noncoding stomach adenocarcinoma Stomach Neoplasms stomach tumor TUG1 TUG1 long noncoding RNA, human tumor cell line unclassified drug upregulation Up-Regulation Vascular Endothelial Growth Factor A vasculotropin A VEGFA VEGFA protein, human Xenograft Model Antitumor Assays
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Long noncoding RNA TUG1 upregulates VEGFA to enhance malignant behaviors in stomach adenocarcinoma by sponging miR-29c-3p

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