Treatment allocation strategies for umbrella trials in the presence of multiple biomarkers: A comparison of methods

Umbrella trials are an innovative trial design where different treatments are matched with subtypes of a disease, with the matching typically based on a set of biomarkers. Consequently, when patients can be positive for more than one biomarker, they may be eligible for multiple treatment arms. In pr...

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Bibliographic Details
Main Authors: Grayling, M.J (Author), Ouma, L.O (Author), Wason, J. (Author), Zheng, H. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Ltd 2021
Subjects:
Online Access:View Fulltext in Publisher