A semiparametric modeling approach for analyzing clinical biomarkers restricted to limits of detection

Before biomarkers can be used in clinical trials or patients' management, the laboratory assays that measure their levels have to go through development and analytical validation. One of the most critical performance metrics for validation of any assay is related to the minimum amount of values...

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Bibliographic Details
Main Authors: Dutta, S. (Author), Halabi, S. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Ltd 2021
Subjects:
Online Access:View Fulltext in Publisher