A semiparametric modeling approach for analyzing clinical biomarkers restricted to limits of detection
Before biomarkers can be used in clinical trials or patients' management, the laboratory assays that measure their levels have to go through development and analytical validation. One of the most critical performance metrics for validation of any assay is related to the minimum amount of values...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
John Wiley and Sons Ltd
2021
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Subjects: | |
Online Access: | View Fulltext in Publisher |