Anti-inflammatory effect of SGLT-2 inhibitors via uric acid and insulin

Anti-inflammatory effect of SGLT-2 inhibitors via uric acid and insulin

Sodium–glucose cotransporter 2 (SGLT-2) inhibitors (i) reduce cardiovascular and renal events in patients with and without type 2 diabetes (T2D). However, the underlying mechanisms are debated. Low-grade inflammation (LGI) is a key driver of vascular complications, suggested to be attenuated by SGLT...

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Bibliographic Details
Main Authors: Berra, C.C (Author), Ceriello, A. (Author), de Candia, P. (Author), Ferroni, S. (Author), Giuliani, A. (Author), La Grotta, R. (Author), Mancino, M. (Author), Matacchione, G. (Author), Olivieri, F. (Author), Prattichizzo, F. (Author), Rippo, M.R (Author), Rispoli, F. (Author), Tagliabue, E. (Author)
Format: Article
Language:English
Published: Springer Science and Business Media Deutschland GmbH 2022
Subjects:
Cardiovascular diseases
Diabetes complications
IL-6
Insulin
Ketones
Kidney disease
Low-grade inflammation
Sodium–glucose cotransporter 2 inhibitors
Uric acid
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