Treatment-induced shrinking of tumour aggregates: a nonlinear volume-filling chemotactic approach
Motivated by experimental observations in 3D/organoid cultures derived from glioblastoma, we propose a novel mechano-transduction mechanism where the introduction of a chemotherapeutic treatment induces mechanical changes at the cell level. We analyse the influence of these individual mechanical cha...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Springer Science and Business Media Deutschland GmbH
2021
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Subjects: | |
Online Access: | View Fulltext in Publisher |