An investigation of tuberculosis progression revealing the role of macrophages apoptosis via sensitivity and bifurcation analysis

An investigation of tuberculosis progression revealing the role of macrophages apoptosis via sensitivity and bifurcation analysis

Mycobacterium tuberculosis infection features various disease outcomes: clearance, latency, active disease, and latent tuberculosis infection (LTBI) reactivation. Identifying the decisive factors for disease outcomes and progression is crucial to elucidate the macrophages-tuberculosis interaction an...

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Bibliographic Details
Main Authors: Ellingson, L. (Author), Frascoli, F. (Author), Heffernan, J. (Author), Zhang, W. (Author)
Format: Article
Language:English
Published: Springer Science and Business Media Deutschland GmbH 2021
Subjects:
apoptosis
Apoptosis
basic reproduction number
Basic Reproduction Number
computer simulation
Computer Simulation
Disease progression
human
Humans
In-host tuberculosis infection model
macrophage
Macrophages
Mycobacterium tuberculosis
Sensitivity analysis and bifurcation analysis
tuberculosis
Tuberculosis
Tuberculosis treatments
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