Dimensionality reduction via path integration for computing mRNA distributions
Inherent stochasticity in gene expression leads to distributions of mRNA copy numbers in a population of identical cells. These distributions are determined primarily by the multitude of states of a gene promoter, each driving transcription at a different rate. In an era where single-cell mRNA copy...
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| Format: | Article |
| Language: | English |
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Springer Science and Business Media Deutschland GmbH
2021
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| Online Access: | View Fulltext in Publisher |