Selective involution of thymic medulla by cyclosporine A with a decrease of mature thymic epithelia, XCR1+ dendritic cells, and epithelium-free areas containing Foxp3+ thymic regulatory T cells
Immunosuppressive drugs such as cyclosporine A (CSA) can disrupt thymic structure and functions, ultimately inducing syngeneic/autologous graft-versus-host disease together with involuted medullas. To elucidate the effects of CSA on the thymus more precisely, we analyzed the effects of CSA on the th...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Springer Science and Business Media Deutschland GmbH
2021
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Subjects: | |
Online Access: | View Fulltext in Publisher |