A computational framework for modeling cell–matrix interactions in soft biological tissues

Living soft tissues appear to promote the development and maintenance of a preferred mechanical state within a defined tolerance around a so-called set point. This phenomenon is often referred to as mechanical homeostasis. In contradiction to the prominent role of mechanical homeostasis in various (...

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Bibliographic Details
Main Authors:	Aydin, R.C (Author), Cyron, C.J (Author), Eichinger, J.F (Author), Grill, M.J (Author), Humphrey, J.D (Author), Kermani, I.D (Author), Wall, W.A (Author)
Format:	Article
Language:	English
Published:	Springer Science and Business Media Deutschland GmbH 2021
Subjects:	Actin Cytoskeleton actin filament Article biological model Biomechanical Phenomena biomechanics cell communication Cell Communication cell density cell matrix interaction cell–extracellular matrix interaction chemistry collagen Collagen Computational framework computer language computer simulation Computer Simulation conceptual framework controlled study cross linking cytoskeleton Cytoskeleton degradation discrete fiber model elastin Elastin Extracellular fibers Extracellular matrices extracellular matrix Extracellular Matrix finite element analysis Finite Element Analysis finite element method growth and remodeling Histology homeostasis Homeostasis human Humans integrin Integrins Markov chain mathematical computing mechanical homeostasis Mechanical homeostasis mechanical stress Mechanisms metabolism Micromechanical mechanisms Models, Biological Molecular clutches Physiological process physiology Programming Languages Proteins rigidity Soft biological tissue soft tissue Stochastic Processes Stress, Mechanical tension Three dimensional computer graphics Tissue
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A computational framework for modeling cell–matrix interactions in soft biological tissues

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