Hyperactivity in mice lacking one allele of the glutamic acid decarboxylase 67 gene

GABAergic interneuron loss, maturational delay or imbalance of glutamatergic to GABAergic signaling has been implicated in several neuropsychiatric disorders including Tourette syndrome and attention-deficit/hyperactivity disorder (ADHD). In schizophrenia, decreases in parvalbumin (PV), somatostatin...

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Bibliographic Details
Main Author:	Smith, K.M (Author)
Format:	Article
Language:	English
Published:	Springer-Verlag Wien 2018
Subjects:	ADHD allele Alleles animal animal behavior animal experiment animal model Animals anxiety Article attention deficit disorder Behavior, Animal cell maturation controlled study disease model Disease Models, Animal DNA isolation elevated plus maze test experimental behavioral test female Female FGFR GABA gene genetics genotype Gilles de la Tourette syndrome glutamate decarboxylase Glutamate Decarboxylase glutamate decarboxylase 1 glutamate decarboxylase 65 glutamic acid decarboxylase 67 gene hyperactivity hyperkinesia Hyperkinesis locomotion male Male Mice Mice, Transgenic mouse nerve cell nonhuman open field test parvalbumin Parvalbumin polymerase chain reaction priority journal schizophrenia somatostatin transgenic mouse
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Hyperactivity in mice lacking one allele of the glutamic acid decarboxylase 67 gene

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