Improved Semiparametric Analysis of Polygenic Gene–Environment Interactions in Case–Control Studies
Standard logistic regression analysis of case–control data has low power to detect gene–environment interactions, but until recently it was the only method that could be used on complex polygenic data for which parametric distributional models are not feasible. Under the assumption of gene–environme...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer
2021
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |