In situ forming phase-inversion implants for sustained ocular delivery of triamcinolone acetonide

In situ forming phase-inversion implants for sustained ocular delivery of triamcinolone acetonide

The objectives of this study were to develop biodegradable poly-lactic-co-glycolic acid (PLGA) based injectable phase inversion in situ forming system for sustained delivery of triamcinolone acetonide (TA) and to conduct physicochemical characterisation including in vitro drug release of the prepare...

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Bibliographic Details
Main Authors: Hong, G.C (Author), Meka, V.S (Author), Sheshala, R. (Author), Thakur, R.R.S (Author), Yee, W.P (Author)
Format: Article
Language:English
Published: Springer Verlag 2019
Subjects:
1 methyl 2 pyrrolidinone
2 pyrrolidone derivative
Administration, Ophthalmic
Article
calibration
chemistry
controlled study
drug formulation
drug implant
Drug Implants
Drug Liberation
drug release
elasticity
Elasticity
glucocorticoid
Glucocorticoids
high performance liquid chromatography
In situ implant
in vitro study
intraocular drug administration
N-methylpyrrolidone
Ocular
optical coherence tomography
Phase inversion
PLGA
polyglactin
Polylactic Acid-Polyglycolic Acid Copolymer
priority journal
Pyrrolidinones
sustained drug release
triamcinolone acetonide
Triamcinolone acetonide
Triamcinolone Acetonide
viscoelasticity
viscometry
viscosity
Viscosity
water transport
Young modulus
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