Quantification of endocannabinoids in human cerebrospinal fluid using a novel micro-flow liquid chromatography-mass spectrometry method

Quantification of endocannabinoids in human cerebrospinal fluid using a novel micro-flow liquid chromatography-mass spectrometry method

The endocannabinoid system (ECS) is implicated in various brain disorders. Changes in the composition of the cerebrospinal fluid (CSF) may be associated with ECS-related pathologies. Endocannabinoids (eCBs) and their analogues are present at low concentrations in human CSF, which hampered the invest...

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Bibliographic Details
Main Authors: Di, X. (Author), Guled, F. (Author), Hankemeier, T. (Author), Harder, A.V.E (Author), Harms, A. (Author), He, B. (Author), Kohler, I. (Author), Krekels, E.H.J (Author), Ramautar, R. (Author), Terwindt, G.M (Author), van den Maagdenberg, A.M.J.M (Author)
Format: Article
Language:English
Published: Elsevier B.V. 2022
Subjects:
Brain
Brain disorders
Cerebrospinal fluid
Down-scaling
Down-scaling analyse
Down-scaling analysis
Endocannabinoid
Endocannabinoids
Human cerebrospinal fluid
LC-MS-MS
Liquid chromatography
Liquid chromatography - mass spectrometries
Mass spectrometry
Micro-flow
Micro-LC-MS
Scaling analysis
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