3D TECA hydrogel reduces cellular senescence and enhances fibroblasts migration in wound healing

3D TECA hydrogel reduces cellular senescence and enhances fibroblasts migration in wound healing

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This study was designed to investigate the effect of 3D TECA hydrogel on the inflammatory-induced senescence marker, and to assess the influence of the gel on the periodontal ligament fibroblasts (PDLFs) migration in wound healing in vitro. PDLFs were cultured with 20 ng/ml TNF-α to induce inflammat...

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Bibliographic Details
Main Authors: Abu Hassan, M.I (Author), Bustami, T.J (Author), Taiyeb Ali, T.B (Author), Younis, L.T (Author)
Format: Article
Language:English
Published: Shenyang Pharmaceutical University 2018
Subjects:
3D TECA
4',6 diamidino 2 phenylindole
5 ethynyl 2' deoxyuridine
Article
beta galactosidase
cell aging
cell migration
cell proliferation
Cellular senescence
Centella asiatica
Centella asiatica extract
chromatin
chromatin condensation
controlled study
deoxyuridine derivative
DNA synthesis
drug design
drug effect
enzyme activity
fibroblast
fibroblast culture
Fibroblast migration
fluorescent dye
histochemistry
human
human cell
hydrogel
in vitro study
inflammation
migration
periodontal ligament
SA-β-gal
staining
TNF-α
tumor necrosis factor
unclassified drug
wound healing
wound healing assay
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