Decreased expression of airway epithelial Axl is associated with eosinophilic inflammation in severe asthma

Decreased expression of airway epithelial Axl is associated with eosinophilic inflammation in severe asthma

Background: Airway epithelium-derived cytokines are critical to provoke and perpetuate type 2 inflammation in asthma. Yet it is poorly understood how this epithelial cell-driven inflammatory response is negatively regulated. We previously reported that Axl receptor tyrosine kinase was expressed by b...

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Bibliographic Details
Main Authors: Aizawa, H. (Author), Fujino, N. (Author), Hussell, T. (Author), Ichikawa, T. (Author), Ichinose, M. (Author), Itakura, K. (Author), Kamide, Y. (Author), Kyogoku, Y. (Author), Matsumoto, S. (Author), Numakura, T. (Author), Okutomo, K. (Author), Ono, Y. (Author), Saito, I. (Author), Saito, T. (Author), Sugiura, H. (Author), Taniguchi, M. (Author), Tsukita, Y. (Author), Yamada, M. (Author)
Format: Article
Language:English
Published: Japanese Society of Allergology 2022
Subjects:
Airway
Asthma
Axl receptor tyrosine kinase
Eosinophilic inflammation
Granulocyte-macrophage colony-stimulating factor
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