Mechanism of antagonistic effects of Andrographis paniculata methanolic extract against Staphylococcus aureus

Mechanism of antagonistic effects of Andrographis paniculata methanolic extract against Staphylococcus aureus

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Objective To investigate the effects of Andrographis paniculata (Burm.f.) Wall. Ex Nees (A. paniculata) on expressions and activities of catalase, superoxide dismutase and alkylhydroperoxide reductase C in Staphylococcus aureus (S. aureus) with respect to its survival in vitro. Methods Antioxidative...

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Bibliographic Details
Main Authors: Hussain, R.M (Author), Mustakim, M. (Author), Razak, Z.N.R.A (Author), Saad, W.M.M (Author)
Format: Article
Language:English
Published: Elsevier (Singapore) Pte Ltd 2017
Subjects:
ahpC gene
alkylhydroperoxide reductase C
Andrographis paniculata
Andrographis paniculata extract
Antagonistic effects
antibacterial activity
antioxidant
antioxidant activity
Article
bacterial cell
bacterial survival
catalase
Catalase
controlled study
down regulation
enzyme activity
gene expression
genetic code
hydrogen peroxide
hydroperoxide
in vitro study
katA gene
minimum inhibitory concentration
nitroblue tetrazolium test
nonhuman
Oxidative stress resistance
oxidoreductase
priority journal
quantitative analysis
real time polymerase chain reaction
sodA gene
sodM gene
Staphylococcus aureus
superoxide dismutase
Superoxide dismutase
unclassified drug
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