Synthesis, in vitro antimicrobial, anticancer evaluation and QSAR studies of N'-(substituted)-4-(butan-2-lideneamino)benzohydrazides

Synthesis, in vitro antimicrobial, anticancer evaluation and QSAR studies of N'-(substituted)-4-(butan-2-lideneamino)benzohydrazides

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A series of N'-(substituted)-4-(butan-2-ylideneamino)benzohydrazides (1-21) was synthesized and characterized by physicochemical as well as spectral means. The synthesized compounds were screened for their in vitro antimicrobial and anticancer potentials. The synthesized compounds displayed hig...

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Bibliographic Details
Main Authors: Kumar, M. (Author), Kumar, P. (Author), Majeed, A.B.A (Author), Mani, V. (Author), Mishra, R.K (Author), Narasimhan, B. (Author), Ramasamy, K. (Author), Saini, M. (Author)
Format: Article
Language:English
Published: Elsevier 2014
Subjects:
Anticancer
Anticancer potentials
Antimicrobial
Anti-microbial activity
Benzohydrazides
Chemical engineering
Chemistry
Microorganisms
Molecular connectivity indexes
QSAR
Topological parameters
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