Direct evidence for the age-dependent demise of GNAS-mutated cells in oral fibrous dysplasia
Objective: Fibrous dysplasia (FD) is a benign bone disease characterized by fibro-osseous lesions. FD is caused by somatic mutations in the gene, guanine nucleotide-binding protein, alpha stimulating activity polypeptide 1 (GNAS), which encodes the G protein subunit, Gsα. FD manifests early in life,...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier Ltd
2018
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Subjects: | |
Online Access: | View Fulltext in Publisher |