Deletion of the T-box transcription factor gene, Tbx1, in mice induces differential expression of genes associated with cleft palate in humans
Objective: We examined the function of the T-box transcription factor 1 (TBX1) in palatogenesis. Design: Tbx1-knockout mice were histologically examined by hematoxylin and eosin staining. Next, secondary palatal shelves dissected from wild type or Tbx1-knockout mice embryos at embryonic day 13.5 wer...
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Format: | Article |
Language: | English |
Published: |
Elsevier Ltd
2018
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Subjects: | |
Online Access: | View Fulltext in Publisher |