Effect of calcium fluoride on the activity of dentin matrix-bound enzymes

Effect of calcium fluoride on the activity of dentin matrix-bound enzymes

Objective: Matrix metalloproteinases (MMPs) and cysteine cathepsins (CCs) are two distinct enzymatic pathways responsible for the degradation of collagen fibrils in demineralized dentin. NaF and KF have been shown to inhibit salivary MMP-2, -9 and CCs. This study investigated the inhibitory effect o...

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Bibliographic Details
Main Authors: Altinci, P. (Author), Mutluay, M. (Author), Tezvergil-Mutluay, A. (Author), Tjäderhane, L. (Author)
Format: Article
Language:English
Published: Elsevier Ltd 2018
Subjects:
anticaries agent
CaF2
calcium fluoride
Calcium Fluoride
Cariostatic Agents
cathepsin
Cathepsins
collagen
Collagen
Collagen degradation
Cysteine cathepsins
Demineralized Dentin Matrix
dentin
Dentin
Dentin matrix
drug effect
enzymology
human
Humans
in vitro study
In Vitro Techniques
matrix metalloproteinase
Matrix Metalloproteinases
metabolism
MMPs
Molar
molar tooth
protein degradation
Proteolysis
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