Insights into the behavior of unsaturated diacylglycerols in mixed lipid bilayers in relation to protein kinase C activation-A molecular dynamics simulation study

The lipid second messenger diacylglycerol (DAG) is known for its involvement in many types of cellular signaling, especially as an endogenous agonist for protein kinase C (PKC). Evidence has emerged that the degree of saturation of the DAG molecules can affect PKC activation. DAG molecules with diff...

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Bibliographic Details
Main Authors: Bunker, A. (Author), Heinonen, S. (Author), Koivuniemi, A. (Author), Lautala, S. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
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Online Access:View Fulltext in Publisher