Crystal structure of SARS-CoV 3C-like protease with baicalein
The 3C-like protease (Mpro, 3CLpro) plays a key role in the replication process in coronaviruses (CoVs). The Mpro is an essential enzyme mediates CoVs replication and is a promising target for development of antiviral drugs. Until now, baicalein has been shown the specific activity for SARS-CoV Mpro...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier B.V.
2022
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Subjects: | |
Online Access: | View Fulltext in Publisher |