Crystal structure of SARS-CoV 3C-like protease with baicalein

The 3C-like protease (Mpro, 3CLpro) plays a key role in the replication process in coronaviruses (CoVs). The Mpro is an essential enzyme mediates CoVs replication and is a promising target for development of antiviral drugs. Until now, baicalein has been shown the specific activity for SARS-CoV Mpro...

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Bibliographic Details
Main Authors: Feng, J. (Author), Li, D. (Author), Li, J. (Author), Yin, X. (Author), Zhang, J. (Author)
Format: Article
Language:English
Published: Elsevier B.V. 2022
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