Synergistic effect of IFN-γ and IL-1β on PD-L1 expression in hepatocellular carcinoma

Immunotherapy using anti-programmed death 1 ligand 1 (PD-L1) antibodies has shown clinical efficacy against hepatocellular carcinoma (HCC) and is recognized as the first-line treatment for unresectable HCC. PD-L1 expression is affected by various cytokines produced by immune cells in the tumor micro...

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Bibliographic Details
Main Authors: Akutsu, N. (Author), Ishigami, K. (Author), Koide, H. (Author), Motoya, M. (Author), Nakase, H. (Author), Numata, Y. (Author), Sasaki, S. (Author), Wagatsuma, K. (Author)
Format: Article
Language:English
Published: Elsevier B.V. 2022
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