Hydrogels with stiffness-degradation spatial patterns control anisotropic 3D cell response

Hydrogels with stiffness-degradation spatial patterns control anisotropic 3D cell response

In nature, tissues are patterned, but most biomaterials used in human applications are not. Patterned biomaterials offer the opportunity to mimic spatially segregating biophysical and biochemical properties found in nature. Engineering such properties allows to study cell-matrix interactions in anis...

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Bibliographic Details
Main Authors: Amini, S. (Author), Cipitria, A. (Author), Duda, G.N (Author), Garrido, C.A (Author), Garske, D.S (Author), Real, S. (Author), Schmidt-Bleek, K. (Author), Thiele, M. (Author)
Format: Article
Language:English
Published: Elsevier Ltd 2023
Subjects:
3d cell-matrix interaction
3D cell-matrix interaction
Anisotropic cell response
Anisotropy
Biomaterials
Cell culture
Cell engineering
Cell matrix interactions
Cell morphology
Cell response
Cells
Crosslinking
Degradability
Degradation
Hydrogels
Image-based
Image-based quantification tool
Morphology
Peptides
Spatial patterns
Stiffness
Stiffness degradation
Stiffness matrix
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