Label-free detection of transport kinetics and inhibitor binding of membrane transport proteins with a two-mode plasmonic sensor

Label-free detection of transport kinetics and inhibitor binding of membrane transport proteins with a two-mode plasmonic sensor

Membrane transporters translocate molecules across cell membranes and are involved in a variety of cellular processes. However, there is still no label-free technique for measuring the transport kinetics of non-charged species through membrane transporters. Here, we develop a new method based on sur...

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Bibliographic Details
Main Authors: Chang, S.-Y (Author), Chao, L. (Author), Hsiao, K.-H (Author), Kuo, C.-J (Author), Kuo, C.-W (Author), Kuo, T.-H (Author), Lee, H.-A (Author), Lin, T.-R (Author), Lin, Y.-T (Author), Tanady, K. (Author), Yang, M.-H (Author)
Format: Article
Language:English
Published: Elsevier Ltd 2022
Subjects:
Biosensor
Glucose
Gold
Kinetics
Label-free detection
Lanthanum compounds
Ligand binding
Ligands
Membrane transporter
Membrane transporters
Membranes
Metallic films
Plasmon waveguide resonances
Plasmonic chip
Plasmonics
Refractive index
Sensor chips
Silica
Silica layers
Surface plasmon resonance
Surface-plasmon resonance
Transport kinetic
Transport kinetics
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