Morphology changes induced by intercellular gap junction blocking: A reaction-diffusion mechanism

Morphology changes induced by intercellular gap junction blocking: A reaction-diffusion mechanism

Complex anatomical form is regulated in part by endogenous physiological communication between cells; however, the dynamics by which gap junctional (GJ) states across tissues regulate morphology are still poorly understood. We employed a biophysical modeling approach combining different signaling mo...

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Bibliographic Details
Main Authors: Cervera, J. (Author), Levin, M. (Author), Mafe, S. (Author)
Format: Article
Language:English
Published: Elsevier Ireland Ltd 2021
Subjects:
agents interacting with transmitter, hormone or drug receptors
algorithm
Algorithms
anatomy and histology
animal
Animals
Article
biological model
cell
cell component
cell junction
controlled study
diffusion
Diffusion
diffusion coefficient
gap junction
Gap junction
Gap Junctions
gene regulatory network
genome
growth, development and aging
induced response
Information
information processing
Intercellular Junctions
ion
Ions
metabolism
Models, Biological
morphogen
morphogenesis
Morphogenesis
morphology
Morphology
Neurotransmitter Agents
nonhuman
outcome assessment
Physiological
physiology
Planaria
Planarians
protein degradation
reaction diffusion model
Reaction-diffusion
regionalization
signal transduction
Signal Transduction
steady state
Turbellaria
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Internet

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