Genomic analysis to assess disease progression and recurrence in patients with oral squamous cell carcinoma: – a preliminary study

We studied the progression from dysplasia to invasive carcinoma and subsequent second primaries or locoregional recurrences in 11 patients with recurrent squamous cell carcinoma (SCC). Between one and six samples were sequenced/patient. DNA samples were prepared, and libraries multiplexed to between...

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Bibliographic Details
Main Authors:	Chengot, P. (Author), Glover, A. (Author), Ho, M.W (Author), Kanatas, A. (Author), Ong, T.K (Author), Sethi, N. (Author), Taylor, M. (Author), Wood, H.M (Author)
Format:	Article
Language:	English
Published:	Churchill Livingstone 2018
Subjects:	Article cancer growth cancer patient cancer recurrence cancer survival carcinogenesis Carcinoma, Squamous Cell chromosome 11 chromosome 5 chromosome 7 chromosome 9 chromosome deletion clinical feature comparative study controlled study disease exacerbation Disease Progression DNA DNA sequence DNA sequencing dysplasia gene dosage genetics genomics Genomics human human cell human genome Humans major clinical study mouth Mouth Neoplasms mouth squamous cell carcinoma mouth tumor neck metastasis Neoplasm Recurrence, Local Oral cancer Oral dysplasia overall survival pathology primary tumor Recurrence recurrent disease Sequence Analysis, DNA squamous cell carcinoma Squamous cell carcinoma time factor Time Factors tumor recurrence
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Genomic analysis to assess disease progression and recurrence in patients with oral squamous cell carcinoma: – a preliminary study

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