Early prediction of incident liver disease using conventional risk factors and gut-microbiome-augmented gradient boosting

Early prediction of incident liver disease using conventional risk factors and gut-microbiome-augmented gradient boosting

The gut microbiome has shown promise as a predictive biomarker for various diseases. However, the potential of gut microbiota for prospective risk prediction of liver disease has not been assessed. Here, we utilized shallow shotgun metagenomic sequencing of a large population-based cohort (N > 7,...

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Bibliographic Details
Main Authors: Åberg, F. (Author), Cheng, S. (Author), Havulinna, A.S (Author), Inouye, M. (Author), Jain, M. (Author), Jousilahti, P. (Author), Knight, R. (Author), Lahti, L. (Author), Liu, Y. (Author), Loomba, R. (Author), Méric, G. (Author), Niiranen, T. (Author), Ruuskanen, M. (Author), Salomaa, V. (Author), Sanders, J. (Author), Teo, S.M (Author), Tripathi, A. (Author), Vázquez-Baeza, Y. (Author), Verspoor, K. (Author), Zhu, Q. (Author)
Format: Article
Language:English
Published: Cell Press 2022
Subjects:
disease
gut
liver disease
metagenomics
microbiome
microbiota
prediction
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