Microbiota alterations in proline metabolism impact depression

Microbiota alterations in proline metabolism impact depression

The microbiota-gut-brain axis has emerged as a novel target in depression, a disorder with low treatment efficacy. However, the field is dominated by underpowered studies focusing on major depression not addressing microbiome functionality, compositional nature, or confounding factors. We applied a...

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Main Authors: Arnoriaga-Rodríguez, M. (Author), Biarnés, C. (Author), Blasco, G. (Author), Brugada, R. (Author), Burokas, A. (Author), Castells-Nobau, A. (Author), Coll, C. (Author), de la Vega-Correa, L. (Author), Deco, G. (Author), Escrichs, A. (Author), Fernández-Real, J.M (Author), Garre-Olmo, J. (Author), Gich, J. (Author), Jové, M. (Author), Maldonado, R. (Author), Martin, M. (Author), Mayneris-Perxachs, J. (Author), Moreno-Navarrete, J.M (Author), Moya, A. (Author), Pamplona, R. (Author), Pedraza, S. (Author), Pérez-Brocal, V. (Author), Portero-Otin, M. (Author), Puig, J. (Author), Ramió-Torrentà, L. (Author), Ramos, R. (Author), Ricart, W. (Author), Serena, J. (Author), Sol, J. (Author), Vilanova, J.C (Author), Zapata, C. (Author)
Format: Article
Language:English
Published: Cell Press 2022
Subjects:
amino acids
brain
cognition
depression
diet
gut microbiota
proline
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