Polymorphic landscape of SARS-CoV-2 genomes isolated from Indian population in 2020 demonstrates rapid evolution in ORF3a, ORF8, nucleocapsid phosphoprotein and spike glycoprotein

Polymorphic landscape of SARS-CoV-2 genomes isolated from Indian population in 2020 demonstrates rapid evolution in ORF3a, ORF8, nucleocapsid phosphoprotein and spike glycoprotein

India, with around 15 million COVID-19 cases, recently became the second worst-hit nation by the SARS-CoV-2 pandemic. In this study, we analyzed the mutation and selection landscape of 516 unique and complete genomes of SARS-CoV-2 isolates from India in a 12-month span (from Jan to Dec 2020) to unde...

Full description

Bibliographic Details
Main Authors: Dey, K.K (Author), Dobhal, S. (Author), Negi, V.S (Author), Pal, A. (Author), Savani, V. (Author), Sharma, A.K (Author)
Format: Article
Language:English
Published: Elsevier Ltd 2021
Subjects:
CdS
CDS
codon
Codon
Complete genomes
COVID-19
Diseases
Evolution
Evolution, Molecular
Genes
Genetic distance
Genetic distances
genetics
Genome
Genome, Viral
Glycoproteins
human
Humans
India
molecular evolution
nucleocapsid protein
Nucleocapsid Proteins
Nucleocapsids
Nucleotides
open reading frame
Open Reading Frames
phosphoprotein
Phosphoproteins
Polymorphism, Single Nucleotide
Principal component analysis
SARS
SARS-CoV-2
Selection
single nucleotide polymorphism
Single nucleotide polymorphisms
SNP
virology
virus genome
Viruses
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items