MutCov: A pipeline for evaluating the effect of mutations in spike protein on infectivity and antigenicity of SARS-CoV-2

MutCov: A pipeline for evaluating the effect of mutations in spike protein on infectivity and antigenicity of SARS-CoV-2

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing an outbreak of coronavirus disease 2019 (COVID-19), is a major threat to public health worldwide. Previous studies have shown that the spike protein of SARS-CoV-2 determines viral infectivity and major antigenicity. However, the s...

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Bibliographic Details
Main Authors: Anashkina, A.A (Author), Huang, Y. (Author), Jiang, Q. (Author), Jin, X. (Author), Li, Y. (Author), Luo, M. (Author), Nie, H. (Author), Wang, P. (Author), Xu, C. (Author), Xu, Z. (Author), Xue, G. (Author), Zhou, W. (Author)
Format: Article
Language:English
Published: Elsevier Ltd 2022
Subjects:
Angiotensin-converting enzyme 2
Antigenicity
Antigens
Binding energy
Binding free energy
Coronavirus
Coronaviruses
Free energy
Health risks
Infectivity
Monoclonal antibodies
Mutation
Pipelines
SARS-CoV-2
Severe acute respiratory syndrome coronavirus
Severe acute respiratory syndrome coronavirus 2
Spike protein
Viral infectivity
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