Reassessment of miRNA variant (isomiRs) composition by small RNA sequencing

IsomiRs, sequence variants of mature microRNAs, are usually detected and quantified using high-throughput sequencing. Many examples of their biological relevance have been reported, but sequencing artifacts identified as artificial variants might bias biological inference and therefore need to be id...

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Bibliographic Details
Main Authors: Aparicio-Puerta, E. (Author), Gómez-Martín, C. (Author), Hackenberg, M. (Author), Medina, J.M (Author), Pegtel, D.M (Author), van Eijndhoven, M.A.J (Author)
Format: Article
Language:English
Published: Cell Press 2023
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